Scientists of the University of Montreal (Canada) found that a key role in the formation of metastases in breast cancer plays AXL protein. Blocking this compound can prevent the development of incurable secondary tumors. About it reported in a press release on MedicalXpress.
In some types of breast cancer has a high enzyme activity of HER2, which contributes to the development of aggressive tumors. The disease becomes intractable in the formation of metastases — secondary lesions that form in other tissues and organs from malignant cells entering the bloodstream. They are the cause of 90 percent of all deaths from breast cancer.
The researchers found that a high level of AXL protein in the cells of HER2-positive cancer increases the probability of their detachment from the primary tumor and metastasis. The decrease in activity of the compound increases survival of patients. According to scientists, drugs targeting AXL, will help to prevent the spread of cancer cells in the body and reduce the risk of the formation of new foci of disease.
Video, photo All from Russia.