Identified a key mechanism of aging


Photo: Eduard Korniyenko / Reuters

Scientists from Lancaster University, University College London and Queen Mary College found that aging in roundworms occurs because of a work unwanted genes, and not due to wear and tear of the body. Researchers believe that the same mechanism is present in humans. This publication reports EurekAlert!.

According to experts, the biological processes that are the norm for a young developing organism, continue to occur at a later age, disrupting the homeostasis of the organism. As a result, diseases such as dementia, cancer, disorders of the cardiovascular system and chronic obstructive pulmonary disease.

The researchers analyzed signs of aging in the nematode Caenorhabditis elegans, laboratory strains which live 2-3 weeks. It turned out that one of the main roles played by genes that encode proteins involved in the autophagy process, when a cell recycles its own components. It turned out that in the late age of autophagy causes serious deterioration of the intestines and leads to death.

Such processes, when the program development is converted into harmful “quasi-program”, are observed in humans. So, in women, the process of leaching of calcium from bones intended for milk production for breastfeeding, can lead to negative consequences after menopause, including osteoporosis, osteoarthritis and calcination of blood vessels.

Video, photo All from Russia.


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