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Scientists Hong Kong Baptist University found that the metal rhodium can be used for the treatment of triple negative breast cancer, which is considered one of the most aggressive forms of malignant tumors. About it reported in a press release on MedicalXpress.
Breast cancer is the most dangerous type of malignant tumors in women, which annually in the world die 521 a thousand people. There are three varieties of this disease: estrogen-receptor-positive (ER-positive), HER2 – positive and triple negative cancer. The latter, constituting 15 percent of all cases of breast cancer, is the most difficult to treat.
The researchers found that the compounds of rhodium blocking the activity of the lysine-specific demethylase 5A (KDM5A). This enzyme is intensively synthesized in the tissues of cancer and contributes to drug resistance. It is shown that products based on metal, inhibit the growth of cells and also show strong antitumor activity. In addition, the new product was less toxic than existing drugs cisplatin and doxorubicin.
Video, photo All from Russia.