Scientists at the Johns Hopkins University (USA) came to the conclusion that chronic inflammation in middle age contribute to a deterioration of memory and other cognitive functions in the years preceding old age. About it reported in a press release on MedicalXpress.
In the study, which lasted about 20 years, was attended by 12 336 people, whose average age has reached 57 years. In the beginning, experts analyzed blood samples to measure four biomarkers of inflammation — the protein fibrinogen, the number of white blood cells, the content of von Willebrand factor and coagulation factor VIII. These indicators were calculated overall level of inflammation.
Three years later, the experts measured the level of C-reactive protein, whose content in the blood also increases when inflammation. All participants were divided into four groups depending on the General level of inflammation and C-reactive protein. Cognitive ability was tested at baseline, 6-9 years later and at the end of the 20-year period.
It turned out that those who have observed high levels of inflammation that occurred 8 percent impairment of memory and other mental skills. The maximum number of C-reactive protein contributed to a 12 percent deterioration in cognitive abilities. Most strongly addressed memory than with language skills or Executive functions. The experts took into account such extraneous factors as education, heart disease and high blood pressure.
Executive functions are called a number of cognitive processes responsible for the control of behavior. They allow you to develop the behaviour required to achieve a certain goal, are the basis of planning, rational thinking and problem solving.
Video, photo All from Russia.