Photo: Jim Bourg / Reuters
Scientists at the University of Illinois found that free fatty acids in the blood of women contribute to the proliferation and growth of breast cancer cells. This explains the increased risk of cancer after menopause. About it reported in a press release on MedicalXpress.
Experts analyzed blood samples from women in the postmenopausal period, including 37 participants with normal weight, 63 obese, and 21 a woman suffering from early research from obesity, but then lost the extra weight. It turned out that the level of free acids was higher in volunteers with obesity, but was significantly reduced in the process of weight loss.
The researchers then added in culture of primary tumor cells and metastatic ER-positive breast cancer blood isolated from women suffering from obesity. The results showed that malignant tissue was more viable and faster growing. While fatty acids are activated by signaling pathways involving protein complexes of mTOR, to promote the growth and reproduction of cancer cells.
Breast cancer is the most common cancer among women. Annually in the world recorded from 800 thousand to one million new cases of developing this type of cancer.
Video, photo All from Russia.