Image: University of Sheffield
Scientists at the University of Sheffield the Laboratory and the Rutherford-Appleton in the UK have discovered a compound that kills the bacteria resistant to antibiotics. The results of the study will help to develop new therapies to prevent epidemics of incurable infections. About it reported in a press release on Phys.org.
The researchers tested the antimicrobial activity of a series of luminescent binuclear complex compounds with two atoms of ruthenium in the form of pathogenic E. coli Escherichia coli. It is shown that the substance destroys the structure of bacterial membrane, and then injected into the cytoplasm. The connection remains effective even if the microorganisms are multi-drug resistant.
The systems remain safe for eukaryotic organisms even at concentrations several orders of magnitude greater than the minimum concentration, has an inhibitory effect. Luminescent properties of a substance enable us to observe its localization within bacteria cells. The substance affects the body in several ways, thereby reducing the risk of development of resistance in pathogenic microbes.
The superbugs are pathogens that due to widespread and improper use of antibacterial drugs become immune to them. The distribution of strains (pure culture of viruses — approx. “Of the tape.ru”), resistant to antibiotics, a cause for concern leading medical organizations that call for rapid development of new types of treatment.
According to experts, the ineffectiveness of antibiotics is the cause of 25 thousand deaths in Europe alone. According to forecasts, by 2050 more than 10 million people could die annually from superbugs.
Video, photo All from Russia.