Image: American Chemical Society
Scientists at the University of Wuhan in China found that cuttlefish ink contain nanoparticles that significantly inhibit the growth of cancerous tumors in mice. About it reported in a press release on Phys.org.
The nanoparticles have spherical shape and the diameter reaches 10 nm. They have the ability to turn the immune cells-macrophages, M2, with suppressed antitumor function in M1 macrophages, which inhibit the development of cancer. M1 destroy tumor cells via phagocytosis (“digestion”) and activating T-lymphocytes.
In recent years, many researchers engaged in the development and synthesis of small molecules and antibodies that can turn M2 macrophages, are abundantly present in tumors and promotes their growth, to M1 macrophages. At the same time, scientists are developing nanoparticles such as photothermal agents, which on exposure to light and heat locally to destroy the cancer cells. However, the drawback is that these synthetic nanoparticles are expensive and difficult to manufacture.
In experiments, scientists have found that the irradiation of infrared light, the nanoparticles become even more effective and kill more than 90 percent of tumor cells in cultures and in living mice almost completely inhibit the growth of malignant tumors and formation of metastases.
Video, photo All from Russia.