Photo: Children’s Medical Research Institute
Scientists at Children’s medical research Institute in Australia have developed a method for rapid and effective treatment of cancer. About it reported in a press release on MedicalXpress.
Researchers have shown that the subunit of the enzyme telomerase — hTERT (telomerase reverse transcriptase person) — enhances the activity of proteins that protect the DNA of cancer cells. This feature transcriptase was not known earlier and it is a key reason why the suppression of the telomeres does not stop the uncontrolled growth of tumors. Simultaneous suppression of hTERT and telomerase’s ability to elongate the tips of chromosomes, leads to rapid death of cancer cells.
The main function of telomerase is the elongation of telomeres — the end parts of chromosomes that protect DNA from damage caused by the replication of the genetic material during cell division. With each division the telomere length shortens. There is a limit of Halika, which shows how much have reduced end portions to the viability of the cells decreased critically. However, cancer cells avoid this due to high telomerase activity.
At the same time, suppression of telomerase alone was ineffective way of dealing with tumors due to the fact that the cells must go through many cycles of division before the telomeres will be depleted.
Video, photo All from Russia.