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Scientists at mit and Harvard University in the US have identified rare mutations in DNA that are responsible for the sudden death of healthy people from heart failure. About it reported in a press release on MedicalXpress.
The experts have determined the nucleotide sequence of DNA isolated from 600 people who died from sudden cardiac arrest, and 600 control patients. Identified 15 genetic variants that play a key role in the pathology.
The researchers also examined genes 4525 of adults in middle age without any signs of cardiovascular disease and found that 41 people had pathogenic DNA. The risk of death from cardiovascular disease among this group was higher more than three times.
Overall, fatal changes in the genes occur in one percent of adults who have not recorded any symptoms. In the US this corresponds to three million people.
From sudden cardiac arrest every year die 220 000 adults, most of whom have not had any problems with the cardiovascular system.
Video, photo All from Russia.