Photo: Jason Cairnduff / Reuters
Researchers from York University in the UK found as toxins produced during Smoking of cigarettes cause damage to DNA. The scientific results published in a press release on the website MedicalXpress, will help to uncover the cause of bladder cancer and correlation between the disease and Smoking.
Scientists have grown tissue of the bladder in the laboratory and subjected them to exposure to the components of cigarette smoke. After this, the researchers analyzed the DNA of cells to find unique mutations that arose in the course of the experiment. It turned out that Smoking does cause damage to genetic material, however, in the tissues of bladder cancer only a small proportion of mutations arose because of the relevant toxins.
Thus, despite the fact that Smoking is a key risk factor for the development of bladder cancer, direct DNA damage by smoke toxins is unlikely to be the main reason for the formation of these kinds of a malignant tumor. Harmful substances can run other mechanisms, damaging genes, and to involve the family of APOBEC enzymes. These enzymes cause mutations in viruses and are part of the body’s natural defenses, but sometimes they can damage the DNA of healthy cells, causing cancer.
Video, photo All from Russia.