Discovered the cause of the penetration of the coronavirus in the brain

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The virus SARS-CoV-2 penetrates into the brain with protein neuropilin-1. This was reported in a study published in the library of preprints and bioRxiv.

A group of European scientists found that cellular protein neuropilin-1 (NRP1) is the cause of the penetration of the coronavirus in the brain of the media. It managed to find with an autopsy of the deceased from COVID-19 patient in the olfactory epithelium and the bulb found infected with SARS-CoV-2 cells. Experts came to the conclusion that the coronavirus doesn’t grow in the cells of the brain, but it can cause their death.

An experiment in mice confirmed the hypothesis of scientists. Using the intranasal method of administration of the virus they managed to infect COVID-19 experimental animals in the laboratory.

The researchers concluded that the penetration into the body of the future media coronavirus cellular proteins neuropilin-1 and ACE-2. Using the last component of the virus particles are fixed in the upper respiratory tract and begin the process of reproduction. The report said that the findings will help in the creation of a vaccine from a deadly disease.

In may, Spanish neuroscientists explain why men’s mortality rate from coronavirus higher than women’s. According to experts, men are more often dependent on tobacco, which together with obstructive lung disease can increase the enzyme ACE-2, by which the coronavirus is fixed in the body.

Video, photo All from Russia.

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